Sorry but I need more information that that.
What version are you using? (If not the latest, try downloading a new version)
Do you have a customized Toastify.xml? (Delete the xml file to force Toastify to recreate it with default settings)
Are you running Toastify from a location where it has write access? ( By default only your personal folder C:\Users\xxx is write enabled in Vista, not \Program files\)